Sarah Silverman
Self
Nathan Barnatt
Homeless Man (segment "Lisa")
Lauren Lapkus
Girl 5 (segment "Lisa")
John C. Reilly
Father (segment "Ham")
Laura Silverman
Self (segment "Knickers")
Seth Rogen
Officer Durand (segment "Knickers")
Jade Catta-Preta
Mother (segment "Lisa")
Natasha Leggero
Girl 2 (segment "Lisa")
?
Shelby Fero
Girl 1 (segment "Lisa")
Nathan Fielder
Self (segment "Retro Video Arcade")