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COLLECTION · Series · 2025

Common Side Effects

Former high school lab partners Marshall and Frances begin to unravel a conspiracy involving big pharma and the federal government to suppress knowledge of a rare mushroom that may hold the key to curing all the world’s diseases.

Source: TMDB
* 8.4 (296)AnimationComedyDramaFantasyScience FictionUnited States
Creators
Joseph Bennett · Steve Hely
Countries
United States
Studios
Adult Swim · Bandera Entertainment · Green Street Pictures · Williams Street · Tell Me More
Runtime
23 min/ep
Age rating
TV-MA
Release
02/02/2025
Score
8.4 / 10 (296)

Awards and nominations

  • Nominated at Primetime Emmy Awards — Outstanding Animated Program
  • Nominated at Television Critics Association Awards — Common Side Effects
  • Nominated at Television Critics Association Awards — Best New Scripted Series
  • Winner at Television Critics Association Awards — Common Side Effects (Episode: "Pilot")
  • Winner at Television Critics Association Awards — Vincent Tsui (Episode: "Cliff's Edge")
  • Nominated at Television Critics Association Awards — Nicolas Snyder (Episode: "Lakestone Limited")
  • Winner at Television Critics Association Awards — Outstanding Achievement for Writing in an Animated Television/Media Production
  • Winner at Television Critics Association Awards — Outstanding Achievement for Editing in a Television/Media Production
  • Winner at Television Critics Association Awards — Common Side Effects
Where to watch
Streaming
HBO Max Amazon ChannelHBO Max Amazon ChannelYouTube TVYouTube TVAdult SwimAdult SwimHBO MaxHBO Max
With ads
Adult SwimAdult Swim
Buy
Amazon VideoAmazon VideoApple TV StoreApple TV StoreGoogle Play MoviesGoogle Play MoviesFandango At HomeFandango At Home
Seasons and episodes
Season 1
Season 1
10 episodes · 2025
Pilot
Episode 1. Pilot
2025-02-02 · 22 min

Marshall meets his old high school classmate Frances and lets her in on a world-changing secret.

Lakeshore Limited
Episode 2. Lakeshore Limited
2025-02-02 · 23 min

Marshall's forced on the run as the DEA pursues him.

Hildy
Episode 3. Hildy
2025-02-09 · 23 min

Marshall visits an old mentor as new pressures mount.

Dumpsite
Episode 4. Dumpsite
2025-02-16 · 23 min

Frances tracks down Marshall in an unlikely location.

Star-Tel-Lite
Episode 5. Star-Tel-Lite
2025-02-23 · 22 min

Marshall, Frances, and their crazy neighbors deal with the aftermath of a dangerous incident.

In the System
Episode 6. In the System
2025-03-02 · 23 min

Stuck in jail, Marshall faces new threats.

Blowfish
Episode 7. Blowfish
2025-03-09 · 23 min

A chance encounter offers a risky opportunity for escape.

Amelia & Wyatt
Episode 8. Amelia & Wyatt
2025-03-16 · 22 min

Marshall and his new ally make a bold move.

Cliff's Edge
Episode 9. Cliff's Edge
2025-03-23 · 23 min

Marshall's mushroom project grows out of hand.

Raid
Episode 10. Raid
2025-03-30 · 23 min

Dangerous forces converge on Marshall's camp.

Season 2
Season 2
Cast by season
Dave King
Dave King
Marshall Cuso (voice)
Emily Pendergast
Emily Pendergast
Frances Applewhite (voice)
Mike Judge
Mike Judge
Rick Kruger (voice)
Martha Kelly
Martha Kelly
Agent Harrington (voice)
Joseph Lee Anderson
Joseph Lee Anderson
Agent Copano (voice)
Comments

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Keywords
mushroompharmaceutical industrydark comedyconspiracyadult animationgovernment conspiracyintrospectivemiracle curecomedy thrillerambiguous
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