The story of Eleanor Bramwell , a pioneering female doctor in the late nineteenth century, and the struggles she has with her friends, her colleagues and society. Determined to take the medical profession out of the dark ages, her strongly held opinions often draw her into conflict with the chief surgeon, a man keener on tradition than he is on progress.

The series begins in 1895 with Dr. Eleanor Bramwell, working in a London hospital. She is treated as an inferior by the male doctors, and her opinions are often ignored. After a disagreement with a senior doctor, Eleanor is dismissed. Her father, Dr. Robert Bramwell, recommends she join him in his private practice of rich, elderly clients. Fortunately,…
The year is 1895, the place is London. Recently qualified doctor Eleanor Bramwell has an observational position in the East London Hospital, but faces resistance from the almost exclusively male medical profession, especially Sir Herbert…
The Thrift is not yet fully operational, but an emergency patient, Frank Harrison, is brought in with a serious burn on his arm. When he returns the next day asking for more morphine, Eleanor realises he has a more serious ailment. He is…
When a woman, Clare Carter, arrives at the Thrift in labour, Lady Cora recognises her as her laundrywoman. Though she claims the father of her baby is a sailor at sea, a man soon arrives claiming to be her husband. The staff initially do…
A young boy, Tom, is brought into the Thrift with injuries suffered when he fell from a ladder after being sent down a sewer. His employer had abandoned him, and it was only one of the other workers who rescued Tom. The poor little waif…
Robert is pursuing research in electrotherapy, and receives the enthusiastic backing of an octogenarian member of his club, who not only wants to finance the experiments, but also to be a subject of them. While canvassing the East London…
The Thrift has been in operation for some months now, and the strain of too much work with too few staff is beginning to show. Lady Cora is acting as administrator, but she is feeling decidedly unwell. When a 16-year-old labourer, Wilf,…
Robert, not yet accustomed to his new duties at the Thrift, has forgotten to deal with the payroll. Instead, he has gone to a bare-knuckle boxing match at his old regiment, where he is trying to do some match-making for his daughter with…

In the Second Series, The Thrift attempts to survive without Lady Peters' guidance, management and financial assistance. A new character, Dr. Finn O'Neill is introduced when a cholera epidemic occurs in the area and Finn assists in the hospital.
On their way to an auction to bid for a building neighbouring the Thrift, Robert and Eleanor are caught up in a horrific train crash on the underground near King William Street station. Robert suffers a broken arm, and so is only able to…
The Thrift has now been in operation for over a year, and Eleanor thinks it may be time to move on. She applies for a part-time position at St. Jude's Hospital, where she runs into the expected opposition, spearheaded by the charismatic…
Robert is celebrating his impending election as a Fellow the Royal College of Physicians, thanks to his old friend Sir William Fredericks. Sir William's son, Martin, plans to go to medical school and is being given the opportunity of…
When Lord Palfrey, from whom Eleanor hopes a substantial donation, arrives for a guided tour of the Thrift, every patient in sight seems to be practicing projectile vomiting. Eleanor thinks it's food poisoning, but Robert diagnoses…
A Bramwell family friend (a former military colleague of Robert), Guy le Saux, returns to London from Canada with a new wife half his age, whom Guy had ""selected"" from a Canadian orphanage. Guy confides in Robert that certain aspects on…
It is February 1896, and a Valentine card arrives, addressed to ""Dr. Bramwell"". Robert assumes (wrongly) that it is meant for him, but cannot imagine who might have sent it. Meanwhile, old Nanny Pat arrives for a visit, and immediately…
Charles Sheldon, a supplier of surgical equipment to the Thrift, arrives with an emergency casualty, a flamboyantly dressed young woman who he says ran out in front of his carriage. When Eleanor examines the patient, she is shocked to…
It is still late winter, 1896, and the Bramwells have gone to Eastbourne for a short break. Robert returns to London, but Eleanor stays on for a few days on her own. Or so she claims. In fact, she has (to every viewer's astonishment!)…

Series Three begins a year after Finn's leaving. He has returned to England for a conference and takes this opportunity to visit Eleanor. Eleanor confirms that she still wishes to be married to Finn in a year when he permanently returns to England. Mr. Marsham considers taking a better position in Edinburgh, but remains at The Thrift.
It is the sweltering summer of 1896, and serious industrial accidents amongst the overworked, underpaid employees of the local brewery are on the rise, partly due to the fact that they are slaking their thirst while on the job. Eleanor is…
Robert has been invited by wealthy Alice Costigan to her country house for a shooting party. He has high hopes of furthering his personal relationship with his hostess, but soon discovers that he has a rival for her affections, in the…
Fed up with endless self-sacrifice and hoping to improve life for the family he has been neglecting, Joe Marsham has decided to accept the much better-paid position in Edinburgh he has been offered. But then he discovers a secret that his…
It is June 1897 and Queen Victoria's Diamond Jubilee celebration will be held in a few days, on the 22nd. The Thrift plans a party, but Eleanor is far more excited by the prospect of Finn O'Neill's return from America, so that they can at…
Eleanor has fled to the country and so Robert finds himself temporarily in charge of the Thrift. At Alice Costigan's suggestion, and against the advice of Dr. Marsham, he hires a young trainee, Charlotte Adler. Her first assignment is to…
Eleanor retreats to the country to recover from the emotional blow dealt her by Dr. O'Neill. She is hosted by old friends from medical-school days, the Kilshaws, whose outwardly blissful existence begins to appear to be concealing a…
Robert has decided to open a Harley Street practice, to which end he borrows the necessary capital through his friend George Talbot, who arranges a very reasonable rate of interest from his banker father-in-law. Unfortunately, that is not…
The apparently miraculous recovery of a hopeless goiter case causes Dr. Marsham to reconsider some of his fundamental convictions. He is reluctant to consider the possibility that a faith healer, Mr. Matthews, may have brought divine…
When Dr. Finn O'Neill returns once again to London, he is famed for his pioneering work with immunization. As a human being, however, he has not improved at all. He sees no reason why he should avoid the Bramwells despite his shameful…
There is joy in the air as Robert Bramwell and Alice Costigan prepare to wed. Unfortunately for Eleanor, her father's impending move to Alice's sumptuous Kew residence also means that he will be withdrawing their support of the Thrift,…

Eleanor allows The Thrift to perform medical check-ups on soldiers, which leads to her meeting Major Quarrie. Eleanor becomes obsessed with locating the child of a patient at The Thrift and searches the slums.
It is October 1899 and the country is gripped by patriotism as the second campaign of the Boer War commences. Eleanor becomes the examining physician for the local Army recruiting station, to the annoyance of more than one officer, as…
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